Bio Active Solvent Free Synthesis of 7,7-dimethyl-4-Phenyl -Tetra Hydro Quinazaloine-(1H,3H)- 2,5-Diones Derivatives Employing Methanesulfonic Acid | Chapter 11 | Challenges and Advances in Chemical Science Vol. 7

Due to its broad variety of biological activities, such as antibacterial and fungicidal activity, the synthesis of 7,-dimethyl-4-phenyl tetrahydroquinazalones- (1H, 3H)-2, 5-diones derivatives has received a lot of attention. The current investigation of an efficient and cost-effective method for the synthesis of 7,7-dimethyl-4-phenyl tetrahydroquinazalones-(1H,3H)-2,5-diones derivatives using dimedone, urea, and substituted aromatic aldehyde using Methanesulfonic acid