Role of Berries and Its Bioactive Compounds in Treating Hypertension: A Review| Chapter 2 | Current Aspects in Pharmaceutical Research and Development Vol. 1

Hypertension, or high blood pressure, is a leading cause of morbidity and mortality in adults, and it is thought to be the primary cause of ischemic heart disease, myocardial necrosis, cardiac failure, renal illness, atherosclerosis, and cerebrovascular accident. Hypertension is known as the “silent killer” since it is an asymptomatic disease with no symptoms in the early stages. As a result, it serves as a substantial risk factor for the development of serious other cardiovascular diseases (CVDs). Because berries are high in polyphenols and bioactive chemicals, they have a lot of potential for treating cardiovascular problems. A polyherbal combination is more better for the treatment of hypertension than a single plant. Methods: The data were gathered by searching PubMed, Medline, ScienceDirect, and Web of Science for research and review publications using search keywords such as “hypertension,” “cardiovascular disease,” “berries,” “cranberry,” and “red raspberry,” as well as all synonyms and related terms. Results: Several studies have linked increased levels of berry flavonoids and other polyphenolic components to a lower risk of cardiovascular disease. Berry’s antioxidant, antihypertensive, anti-sclerotic, and other capabilities, according to scientific evidence, address the characteristics of many biochemical processes. Conclusion: According to this article, there is a global increase in berry consumption nowadays, which is utilised to treat a variety of cardiovascular disorders. The studies are needed to determine the appropriate dose, technique, or method of preparation (formulation), and length of berry intervention so that better therapy alternatives for hypertension can be demonstrated. In comparison to allopathy and any other medication method, the evidence strongly suggests that herbs/plants have a higher efficacy.



Author(s) Details

HOD & Associate Professor, Dr. Ankita Wal
Department of Pharmacology, Institute of Pharmacy, Pranveer Singh Institute of Technology, Kanpur, Uttar Pradesh, India.


Dean & Associate Professor, Dr. Pranay Wal
Department of Pharmacology, Institute of Pharmacy, Pranveer Singh Institute of Technology, Kanpur, Uttar Pradesh, India.


Tamsheel Fatima Roohi
Department of Pharmacology, Institute of Pharmacy, Pranveer Singh Institute of Technology, Kanpur, Uttar Pradesh, India.


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